Bandi e contributi per enti del terzo settore

13942
bandi aperti
9
paesi
12
fonti ufficiali

Raccogliamo in un unico posto i bandi di finanziamento pubblico di Spagna, Unione Europea e altri paesi. Ogni scheda indica l'importo, la scadenza reale e chi può presentare domanda.

Bandi per tipo di ente

Bandi aperti

13.942 bandi · ordinati per In scadenza prima

🇪🇸SpagnaAPERTA
27 giorni

SUBVENCIONES CAMPAMENTOS URBANOS DE VERANO 2026

LOCAL - VILLAMAYOR - AYUNTAMIENTO DE VILLAMAYOR ·

Educación

0 €7/9/2026
Vedi
🇫🇷FranciaAPERTA
27 giorni

Appuyer les initiatives locales de développement solidaire et d’ECSI

Francia · FR

Chi può richiederla Commune · Intercommunalité / Pays · Département · Région · Etablissement public dont services de l'Etat

Ce dispositif finance des projets de solidarité internationale portés par des organismes néo-aquitains. Il soutient deux types de projets et est organisé en 2 axes : les projets d'éducation à la citoyenneté et à la solidarité internationale (ECSI) dans l'axe "COMPRENDRE", et les projets de développement solidaire avec des partenaires de pays éligibles à l'aide publique au développement dans l'axe "AGIR". Dans le cadre de sa feuille de route pour l’action européenne, transfrontalière et internationale 2023-2028, la Région Nouvelle-Aquitaine affirme notamment l’ambition: D’être une région solidaire, inclusive et durable ; De faciliter l’accès à l’Europe et à l’international des opérateurs régionaux; De faire de l’action européenne et internationale un accélérateur de l’innovation sur l’ensemble du territoire. Ce dispositif, renouvelé et unifié en 2026, vise à soutenir: Les projets d’éducation à la citoyenneté et à la solidarité internationale (ECSI) , à l’ouverture au monde, visant la compréhension des enjeux internationaux contemporains et notamment des objectifs de développement durable (ODD) dans une perspective internationale. AXE «COMPRENDRE» Les projets de coopération et de solidarité internationale impliquant un ou plusieurs partenaires internationaux issus d’un ou plusieurs pays éligibles à l’aide publique au développement et s’inscrivant dans une logique de partenariat. Ces projets devront obligatoirement inclure un volet d’ECSI sur le territoire régional au profit des jeunes et/ou du grand public. AXE «AGIR» Il répond aux objectifs suivants : Contribuer, à l’échelle régionale, à l’atteinte d'ici à 2030 des 17 Objectifs de Développement Durable (ODD) pour lutter contre la pauvreté, les inégalités et l’injustice et faire face au changement climatique ; Contribuer à l’atteinte des objectifs de la feuille de route régionale « Néo Terra » dédiée à la transition énergétique et écologique ; Favoriser l’ouverture au monde et une meilleure compréhension des enjeux mondiaux ; Susciter l’engagement des acteurs néo-aquitains en faveur d’une société plus solidaire et responsable et d’un développement soutenable ; Participer à la valorisation des savoir-faire régionaux à l’étranger et à leur enrichissement grâce aux échanges internationaux ; Soutenir le dynamisme de la société civile de Nouvelle-Aquitaine dans la solidarité internationale et l’éducation à la citoyenneté internationale grâce à l'accompagnement d'acteurs associatifs, économiques et institutionnels locaux. Montant maximal : 10 000€ pour les projets de l'axe COMPRENDRE et 40 000€ pour les projets de l'axe AGIR Taux d'aide : la subvention ne pourra pas représenter plus de 50% du Coût Total (CT) du projet Dépenses de personnels salariés plafonnées à 30% du coût total (CT) pour l'axe AGIR et 50% pour l'axe COMPRENDRE ; Dépenses de personnels volontaires plafonnées à 40 % du CT ; Frais de mission à l’étranger plafonnées à 30% du CT ; Frais généraux (ou administratifs) limités à 5% du CT ; Contributions valorisées plafonnées à 20% du CT ; Autofinancement, hors valorisation, d’au moins 5% du CT ; Participation (financière et/ou valorisée) des partenaires internationaux attendue.

Secondo il bando7/9/2026
Vedi
🇪🇸SpagnaAPERTA
27 giorni

Convocatoria Pyme Digital 2026 - Cámara de Comercio de Bilbao

OTROS - CÁMARA DE COMERCIO DE BILBAO ·

Investigación, desarrollo e innovación

179.760 €7/9/2026

Periodo: 12/3/2026

Vedi
🇪🇸SpagnaAPERTA
27 giorni

Convocatoria Pyme Cibersegura 2026 - Cámara de Comercio de Bilbao

OTROS - CÁMARA DE COMERCIO DE BILBAO ·

Investigación, desarrollo e innovación

34.240 €7/9/2026

Periodo: 12/3/2026

Vedi
🇪🇸SpagnaAPERTA
27 giorni

Resol. del 10/2/2026 por la que se aprueban bases reg. para conces. de subv. a las entidades locales, rég. concurrencia no competitiva, dest. realizac. auditorías redes saneamiento para detecc. infiltraciones, conv. 2026 (AU301D)

AUTONOMICA - GALICIA - AGUAS DE GALICIA ·

Otras Prestaciones económicas

500.000 €7/9/2026

Periodo: 6/3/2026

Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Premio di ricerca per tesi di dottorato su uso di sostanze/disturbo da uso di sostanze (R36 studi clinici non consentiti)

Stati Uniti · US

Chi può richiederla Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Special district governments · Public and State controlled institutions of higher education · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Private institutions of higher education · Public housing authorities/Indian housing authorities · State governments · Native American tribal governments (Federally recognized) · For profit organizations other than small businesses · County governments · Native American tribal organizations (other than Federally recognized tribal governments) · City or township governments · Independent school districts · Small businesses

L'obiettivo di questo NOFO è supportare i dottorandi di una varietà di discipline accademiche per un massimo di due anni per il completamento del progetto di ricerca della tesi di dottorato. I progetti di ricerca dovrebbero allinearsi con le priorità di finanziamento del NIDA dettagliate qui (https://www.drugabuse.gov/funding/funding-priorities). Questo premio faciliterà l'ingresso di nuovi promettenti ricercatori nel campo della ricerca sull'uso di sostanze/disturbo da uso di sostanze (SU(D)), aumentando il numero di ricercatori SU(D) di grande talento.

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Alcohol Health Services Research (R01 Clinical Trial Optional)

Stati Uniti · US

Chi può richiederla Public and State controlled institutions of higher education · Small businesses · For profit organizations other than small businesses · Others (see text field entitled "Additional Information on Eligibility" for clarification) · State governments · City or township governments · Special district governments · Native American tribal organizations (other than Federally recognized tribal governments) · County governments · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Public housing authorities/Indian housing authorities · Private institutions of higher education · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Native American tribal governments (Federally recognized) · Independent school districts

The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R01 Clinical Trial Optional mechanism focusing on alcohol health services. This NOFO will broadly focus on closing the treatment gap for individuals with alcohol use disorder (AUD); within this focus, there are five major areas of emphasis: (1) increasing access to treatment for AUD, (2) making treatment for AUD more appealing, (3) examining cost structures and insurance systems, (4) conducting studies on dissemination and implementation of existing evidence-based approaches to treating AUD, and (5) reducing health disparities as a means of addressing the treatment gap in AUD for health disparity populations.

500.000 US$7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Alcohol Treatment, Pharmacotherapy, and Recovery Research (R01 Clinical Trial Required)

Stati Uniti · US

Chi può richiederla Public housing authorities/Indian housing authorities · Private institutions of higher education · State governments · Special district governments · For profit organizations other than small businesses · County governments · Native American tribal governments (Federally recognized) · Public and State controlled institutions of higher education · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Small businesses · Native American tribal organizations (other than Federally recognized tribal governments) · City or township governments · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Independent school districts

The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R01 Clinical Trial Required mechanism focusing on alcohol treatment and recovery research. This NOFO will focus broadly on topics relevant for treatment of and recovery from alcohol use disorder (AUD), including: medications development, precision medicine, behavioral therapies and mechanisms of behavioral change (MOBC), recovery, translational research, and innovative methods and technologies for AUD treatment and recovery.

500.000 US$7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Alcohol Health Services Research (R34 Clinical Trial Optional)

Stati Uniti · US

Chi può richiederla City or township governments · Special district governments · For profit organizations other than small businesses · Small businesses · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Native American tribal organizations (other than Federally recognized tribal governments) · Native American tribal governments (Federally recognized) · State governments · Public and State controlled institutions of higher education · Independent school districts · Public housing authorities/Indian housing authorities · County governments · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Private institutions of higher education

The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R34 Clinical Trial Optional mechanism focusing on alcohol health services. This NOFO will broadly focus on closing the treatment gap for individuals with alcohol use disorder (AUD); within this focus, there are five major areas of emphasis: (1) increasing access to treatment for AUD, (2) making treatment for AUD more appealing, (3) examining cost structures and insurance systems, (4) conducting studies on dissemination and implementation of existing evidence-based approaches to treating AUD, and (5) reducing health disparities as a means of addressing the treatment gap in AUD for health disparity populations.

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Alcohol Treatment, Pharmacotherapy, and Recovery Research (R34 Clinical Trial required)

Stati Uniti · US

Chi può richiederla Native American tribal governments (Federally recognized) · Independent school districts · Private institutions of higher education · Special district governments · Public and State controlled institutions of higher education · County governments · City or township governments · Public housing authorities/Indian housing authorities · Native American tribal organizations (other than Federally recognized tribal governments) · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Others (see text field entitled "Additional Information on Eligibility" for clarification) · For profit organizations other than small businesses · Small businesses · State governments

The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R34 Clinical Trial Optional mechanism focusing on alcohol health services. This NOFO will broadly focus on closing the treatment gap for individuals with alcohol use disorder (AUD); within this focus, there are five major areas of emphasis: (1) increasing access to treatment for AUD, (2) making treatment for AUD more appealing, (3) examining cost structures and insurance systems, (4) conducting studies on dissemination and implementation of existing evidence-based approaches to treating AUD, and (5) reducing health disparities as a means of addressing the treatment gap in AUD for health disparity populations.

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed)

Stati Uniti · US

Chi può richiederla State governments · Public housing authorities/Indian housing authorities · Native American tribal organizations (other than Federally recognized tribal governments) · County governments · City or township governments · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Small businesses · Special district governments · For profit organizations other than small businesses · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Independent school districts · Public and State controlled institutions of higher education · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Private institutions of higher education · Native American tribal governments (Federally recognized)

This Notice of Funding Opportunity (NOFO) encourages research on the biology of high-confidence risk factors associated with complex brain disorders, with a focus on the intracellular, transcellular, and circuit substrates of neural function. For the purposes of this NOFO, the term complex can refer to a multifactorial contribution to risk (e.g., polygenic and/or environmental) and/or highly distributed functional features of the brain disorder. Studies may be either hypothesis-generating (unbiased discovery) or hypothesis-testing in design and may utilize in vivo, in situ or in vitro experimental paradigms, e.g., model organisms or human cell-based assays. While behavioral paradigms and outcome measures can be incorporated into the research design to facilitate the characterization of intracellular, transcellular, and circuit mechanisms, these are neither required nor expected. Studies should not attempt to model disorders but instead should aim to elucidate the neurobiological impact of individual or combined risk factor(s), such as the affected molecular and cellular components and their relationships within defined biological process(es). This can include the fundamental biology of these factors, components, and processes. The resulting paradigms, component pathways, and biological processes should be disseminated with sufficient detail to enrich common and/or federated data resources (e.g., those contributing to the Gene Ontology, Synaptic Gene Ontology, FAIR Data Informatics) in order to bridge the gap between disease risk factors, biological mechanism and therapeutic target identification. The present NOFO (R01 activity code) can be used for applications to further develop lines of inquiry where feasibility or proof-of-concept has been established. Applicants proposing exploratory research at the early and conceptual stages of project development should apply to the companion R21 NOFO PAR-24-025

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Social disconnection and Suicide Risk in Late Life (R21 Clinical Trial Optional)

Stati Uniti · US

Chi può richiederla City or township governments · State governments · Independent school districts · Public housing authorities/Indian housing authorities · Small businesses · Private institutions of higher education · Native American tribal organizations (other than Federally recognized tribal governments) · County governments · Special district governments · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Public and State controlled institutions of higher education · Native American tribal governments (Federally recognized) · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · For profit organizations other than small businesses

This initiative seeks to solicit applications for research projects that address the link between social disconnection including both objective social isolation as well as perceived social isolation (otherwise known as loneliness) and suicide in late-life. Emphasis is placed on research that identifies neurobiological and environmental mechanisms associated with social isolation and loneliness that increase risk for suicidal thoughts and behavior in late-life, that uses an experimental therapeutics approach to identify targets and develop and test interventions to prevent late-life suicide, and that develops new and modifies existing service delivery models to enhance social connection in late-life to prevent suicide.

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)

Stati Uniti · US

Chi può richiederla County governments · Public and State controlled institutions of higher education · Independent school districts · Native American tribal organizations (other than Federally recognized tribal governments) · Special district governments · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · City or township governments · Small businesses · Native American tribal governments (Federally recognized) · Public housing authorities/Indian housing authorities · State governments · Private institutions of higher education · For profit organizations other than small businesses · Others (see text field entitled "Additional Information on Eligibility" for clarification)

Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagnosed and those aging with the illness, the mechanisms underlying the generation and trajectory of the illness remain poorly understood. The purpose of this initiative is to advance translational research to better understand the emergence and trajectory of schizophrenia and related disorders in mid to late life, and to identity targets for future development of prevention and treatment efforts.

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional)

Stati Uniti · US

Chi può richiederla County governments · Private institutions of higher education · Public and State controlled institutions of higher education · Special district governments · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Public housing authorities/Indian housing authorities · For profit organizations other than small businesses · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Independent school districts · Native American tribal organizations (other than Federally recognized tribal governments) · City or township governments · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Small businesses · State governments · Native American tribal governments (Federally recognized)

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowledge of mechanisms associated with neuropsychiatric symptoms (NPS) in persons with Alzheimer's disease (AD) or Alzheimer's disease-related dementias (ADRD). The findings are expected to advance mechanistic understanding of both biobehavioral and neurobiological pathways leading to NPS. Findings may also provide insight into novel therapeutic targets that can be advanced into interventions to treat and prevent the development of NPS in AD and/or ADRD

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)

Stati Uniti · US

Chi può richiederla Public housing authorities/Indian housing authorities · Public and State controlled institutions of higher education · Private institutions of higher education · County governments · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · City or township governments · Special district governments · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · For profit organizations other than small businesses · Native American tribal organizations (other than Federally recognized tribal governments) · Independent school districts · Native American tribal governments (Federally recognized) · Others (see text field entitled "Additional Information on Eligibility" for clarification) · State governments · Small businesses

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowledge of mechanisms associated with neuropsychiatric symptoms (NPS) in persons with Alzheimer's disease (AD) or Alzheimer's disease-related dementias (ADRD). The findings are expected to advanceadavnce mechanistic understanding of both biobehavioral and neurobiologfical pathways leading to NPS. Findings may also provide insight into novel therapeutic targets that can be advanced into interventions to treat and prevent the development of NPS in AD and/or ADRD.

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Schizophrenia and related disorders during mid- to late-life (R01 Clinical Trial Optional)

Stati Uniti · US

Chi può richiederla Native American tribal organizations (other than Federally recognized tribal governments) · State governments · Private institutions of higher education · Special district governments · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Small businesses · City or township governments · Public housing authorities/Indian housing authorities · For profit organizations other than small businesses · Native American tribal governments (Federally recognized) · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · County governments · Public and State controlled institutions of higher education · Independent school districts

Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagnosed and those aging with the illness, the mechanisms underlying the generation and trajectory of the illness remain poorly understood. The purpose of this initiative is to advance translational research to better understand the emergence and trajectory of schizophrenia and related disorders in mid to late life, and to identity targets for future development of prevention and treatment efforts.

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Social disconnection and Suicide Risk in Late Life (R01 Clinical Trial Optional)

Stati Uniti · US

Chi può richiederla County governments · Public and State controlled institutions of higher education · State governments · Native American tribal organizations (other than Federally recognized tribal governments) · For profit organizations other than small businesses · Private institutions of higher education · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Special district governments · Native American tribal governments (Federally recognized) · Public housing authorities/Indian housing authorities · City or township governments · Small businesses · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Independent school districts

This initiative seeks to solicit applications for research projects that address the link between social disconnection including both objective social isolation as well as perceived social isolation (otherwise known as loneliness) and suicide in late-life. Emphasis is placed on research that identifies neurobiological and environmental mechanisms associated with social isolation and loneliness that increase risk for suicidal thoughts and behavior in late-life, that uses an experimental therapeutics approach to identify targets and develop and test interventions to prevent late-life suicide, and that develops new and modifies existing service delivery models to enhance social connection in late-life to prevent suicide.

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Cellular and Molecular Biology of Complex Brain Disorders (R21 Clinical Trial Not Allowed)

Stati Uniti · US

Chi può richiederla City or township governments · State governments · Native American tribal governments (Federally recognized) · County governments · Public and State controlled institutions of higher education · Independent school districts · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Public housing authorities/Indian housing authorities · For profit organizations other than small businesses · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Special district governments · Small businesses · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Native American tribal organizations (other than Federally recognized tribal governments) · Private institutions of higher education

This Notice of Funding Opportunity (NOFO) encourages research on the biology of high confidence risk factors associated with complex brain disorders, with a focus on the intracellular, transcellular and circuit substrates of neural function. For the purposes of this NOFO, the term complex can refer to a multifactorial contribution to risk (e.g., polygenic and/or environmental) and/or highly distributed functional features of the brain disorder. Studies may be either hypothesis-generating (unbiased discovery) or hypothesis-testing in design and may utilize in vivo, in situ, or in vitro experimental paradigms, e.g., model organisms or human cell-based assays. While behavioral paradigms and outcome measures can be incorporated into the research design to facilitate the characterization of intracellular, transcellular and circuit mechanisms, these are neither required nor expected. Studies should not attempt to model disorders but instead should aim to elucidate the neurobiological impact of individual or combined risk factor(s), such as the affected molecular and cellular components and their relationships within defined biological process(es). This can include the fundamental biology of these factors, components and processes. The resulting paradigms, component pathways and biological processes should be disseminated with sufficient detail to enrich common and/or federated data resources (e.g., those contributing to the Gene Ontology, Synaptic Gene Ontology, FAIR Data Informatics) in order to bridge the gap between disease risk factors, biological mechanism and therapeutic target identification. The present NOFO (R21 activity code) can be used for applications to develop early stage, high-risk, exploratory approaches or establish proof-of-concept where there is little or no preliminary data. Applicants proposing to develop lines of inquiry where feasibility or proof of concept has been established should apply to the companion R01 NOFO (PAR-xx-xxx).

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Progetti di ricerca per migliorare l'applicabilità dei modelli mammiferi per la ricerca traslazionale (R01 Clinical Trial Not Allowed)

Stati Uniti · US

Chi può richiederla Native American tribal organizations (other than Federally recognized tribal governments) · County governments · Public housing authorities/Indian housing authorities · State governments · Private institutions of higher education · Public and State controlled institutions of higher education · Native American tribal governments (Federally recognized) · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Special district governments · Small businesses · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · City or township governments · Independent school districts · For profit organizations other than small businesses

Attraverso questo Avviso di Opportunità di Finanziamento (NOFO), il National Cancer Institute (NCI) invita a presentare domande per progetti volti ad espandere, migliorare o trasformare l'utilità dei modelli mammiferi di cancro e tumore per la ricerca traslazionale. Con questo NOFO, l'NCI intende incoraggiare la presentazione di progetti dedicati a dimostrare che i modelli mammiferi o i loro derivati utilizzati per la ricerca traslazionale sono rappresentazioni robuste della biologia umana, sono appropriati per testare questioni di importanza clinica e forniscono informazioni affidabili a beneficio dei pazienti. Questi obiettivi pratici contrastano con gli obiettivi di molti progetti R01 meccanicistici, supportati dall'NCI, che impiegano mammiferi, o sviluppano e utilizzano modelli di cancro mammiferi, modelli di tumore da trapianto, o modelli derivati da tessuti o cellule mammifere o umane per la verifica di ipotesi, ricerca non clinica. Tra le molte altre possibili iniziative, i richiedenti in risposta a questo FOA potrebbero proporre dimostrazioni su come superare le carenze traslazionali dei modelli oncologici mammiferi, definire nuovi usi dei modelli mammiferi o della loro genetica per sfide traslazionali inesplorate, promuovere pratiche standard per l'uso di modelli traslazionali, testare approcci per convalidare e accreditare i modelli, o sfidare le pratiche attuali su come i modelli vengono utilizzati in modo traslazionale.

499.000 US$7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

Sviluppo e screening di saggi per la scoperta di sonde chimiche, farmaci o immunomodulatori (R01 Clinical Trial Not Allowed)

Stati Uniti · US

Chi può richiederla Native American tribal organizations (other than Federally recognized tribal governments) · State governments · Private institutions of higher education · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · For profit organizations other than small businesses · Special district governments · Native American tribal governments (Federally recognized) · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Independent school districts · Public and State controlled institutions of higher education · Small businesses · Public housing authorities/Indian housing authorities · County governments · City or township governments

Attraverso questo Avviso di Opportunità di Finanziamento (NOFO), il National Cancer Institute (NCI) sollecita candidature per l'identificazione di piccole molecole che funzionano per chiarire la biologia della malattia come sonde chimiche o funzionano come agonisti o antagonisti del bersaglio/i della malattia per la terapia o l'immunoterapia. Il NOFO è inteso a supportare la ricerca di scoperta per l'identificazione di hit validati rilevanti per gli esiti correlati alla salute degli Istituti NIH partecipanti. Le fasi della ricerca di scoperta coperte da questo NOFO includono: 1) sviluppo di saggi per specifici bersagli biologici e meccanismi di malattia rilevanti per la missione degli Istituti NIH partecipanti con l'intento di screenare composti a piccole molecole che mostrano potenziale come sonde da utilizzare per far progredire la conoscenza sui bersagli noti, identificare nuovi bersagli o come lead pre-terapeutici; 2) implementazione dello screening con approcci ad alto rendimento focalizzati sul bersaglio o approcci a rendimento moderato basati su fenotipi e frammenti per identificare gli hit di screening iniziali; 3) validazione degli hit, inclusa l'implementazione di saggi secondari ortogonali al saggio primario, analisi cheminformatiche avanzate e ispezione iniziale di chimica medicinale per prioritizzare il set di hit, e saggi di follow-up per caratterizzare la modalità e il meccanismo d'azione degli hit validati; 4) ottimizzazione da hit a lead, inclusa SAR per ottimizzare l'engagement del bersaglio, la selettività e per minimizzare le passività chimiche, studi ADME, PK e PD, e, se appropriato, in vivo m…

Secondo il bando7/9/2026
Vedi
🇺🇸Stati UnitiAPERTA
27 giorni

National Centers for Biomedical Imaging and Bioengineering (NCBIB) (P41 Clinical Trials Optional)

Stati Uniti · US

Chi può richiederla Special district governments · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · State governments · County governments · Independent school districts · Small businesses · City or township governments · Public housing authorities/Indian housing authorities · Public and State controlled institutions of higher education · Others (see text field entitled "Additional Information on Eligibility" for clarification) · Native American tribal governments (Federally recognized) · For profit organizations other than small businesses · Native American tribal organizations (other than Federally recognized tribal governments) · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Private institutions of higher education

This Funding Opportunity Announcement (FOA) encourages grant applications for Biomedical Technology Resource Centers (BTRCs). BTRCs are national resource centers for conducting research and development on new technologies that are driven by the needs of basic, translational, and/or clinical researchers. BTRCs also make their technologies available to other investigators, train members of the research community in the use of the technologies, and disseminate the technologies broadly.

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