Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

Description

The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies). Applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in manufacturing, scaling, pharmacokinetics, toxicology, and Phase I clinical testing. BPN-Biologics awardee institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN-Biologics contractors (and thereby control the patent prosecution and licensing negotiations) for biotherapeutic candidates developed in this program.

Official source

Eligible beneficiaries

• County governments
• Native American tribal organizations (other than Federally recognized tribal governments)
• City or township governments
• Small businesses
• For profit organizations other than small businesses
• Others (see text field entitled "Additional Information on Eligibility" for clarification)
• Public housing authorities/Indian housing authorities
• Private institutions of higher education
• Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
• Public and State controlled institutions of higher education
• State governments
• Special district governments
• Independent school districts
• Native American tribal governments (Federally recognized)
• Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education