Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)

Description

The overarching purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and/or early evaluation of strong candidate biomarkers and biomarker signatures that can be used as tools to facilitate the clinical development of neurotherapeutics and their use in clinical practice. Specifically, the focus of this FOA is on the identification and initial biological, analytical and clinical evaluation of biomarkers and biomarker signatures for neurological and neuromuscular disorders. Although research supported by this FOA can include animal studies, it must also include preliminary human evaluation using carefully standardized human samples or datasets. The goal of this initiative is to deliver candidate biomarkers or biomarker signatures that are ready for definitive analytical and clinical validation studies.

Official source

Eligible beneficiaries

• Others (see text field entitled "Additional Information on Eligibility" for clarification)
• Native American tribal governments (Federally recognized)
• Native American tribal organizations (other than Federally recognized tribal governments)
• Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
• Public and State controlled institutions of higher education
• City or township governments
• Public housing authorities/Indian housing authorities
• Private institutions of higher education
• State governments
• Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
• Independent school districts
• For profit organizations other than small businesses
• County governments
• Special district governments
• Small businesses