Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

Description

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for exploratory and early-stage projects that focus on undruggable target classes within intractable human disease. Applicants will identify a human disease relevant undruggable target class and develop a method or agent that is selective for one or more targets within that target class. This NOFO is intended to jumpstart research that demonstrates innovative strategies to modulate targets that cannot be addressed by established therapeutic types, furthering the development of methods and/or agents selective for undruggable target classes.

Official source

Eligible beneficiaries

• City or township governments
• Public and State controlled institutions of higher education
• State governments
• Others (see text field entitled "Additional Information on Eligibility" for clarification)
• Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
• Private institutions of higher education
• Native American tribal organizations (other than Federally recognized tribal governments)
• County governments
• Special district governments
• Small businesses
• Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
• For profit organizations other than small businesses
• Independent school districts
• Native American tribal governments (Federally recognized)
• Public housing authorities/Indian housing authorities