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🇺🇸GRANTS_GOVOPENGRANT271 days left

Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)

🏛 GRANTS_GOV · 📍 US

Total budget

Not specified

OPENING

Dec 6, 2024

CLOSING

Jul 2, 2027

Category

Health

Description

This notice of funding opportunity (NOFO) provides funding to conduct efficacy studies in an established rare disease preclinical model to demonstrate that a proposed therapeutic agent warrants further development. In addition to preclinical efficacy, accompanying pharmacodynamic and pharmacokinetic studies would be supported. Therapeutic agents include small molecules, biologics or biotechnology-derived products. The goal of this NOFO is to spur therapeutic development for a variety of rare diseases by advancing projects to the point where they would attract subsequent investment supporting full Investigational New Drug (IND) application development or progression to clinical trials in the case of repurposing or repositioning.

Official source

View official source ↗

Eligible beneficiaries

  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Special district governments
  • Public and State controlled institutions of higher education
  • Small businesses
  • Independent school districts
  • City or township governments
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Private institutions of higher education
  • Native American tribal governments (Federally recognized)
  • State governments
  • County governments
  • For profit organizations other than small businesses
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)

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